QSC Peptidology
Research hub

Tirzepatide Research Hub

The GLP-1 and GIP dual agonist: how it compares with semaglutide and retatrutide, how it is handled, and lab vials from 5 mg to 120 mg.

What is tirzepatide?

Tirzepatide is a 39-amino-acid dual agonist that activates both the GLP-1 and GIP receptors. It carries a C20 fatty diacid moiety that binds albumin, which extends its half-life to roughly five days. Its CAS number is 2023788-19-2 and its molecular weight is about 4813.5 Da.

The dual receptor profile produces a stronger metabolic effect than single-receptor analogs in reported animal studies. Common research applications include comparative GLP-1/GIP pathway studies, glucose-tolerance protocols, and adipose-tissue signalling work. QSC supplies tirzepatide strictly for laboratory research.

Table showing that semaglutide activates the GLP-1 receptor, tirzepatide activates GLP-1 and GIP receptors, and retatrutide activates GLP-1, GIP and glucagon receptors

Receptor profiles of semaglutide, tirzepatide and retatrutide as described in the literature.

Start here: research guides

Lab vials

Tirzepatide in eleven vial sizes from 5 mg to 120 mg, plus pre-mixed research blends with cagrilintide and with retatrutide. All are supplied as lyophilized powder in 10-vial packs.

Tirzepatide · Questions

What is tirzepatide?

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Tirzepatide is a 39-amino-acid dual agonist of the GLP-1 and GIP receptors, with a C20 fatty diacid moiety for albumin binding (CAS 2023788-19-2, about 4813.5 Da). It is studied in research on incretin signalling, glucose handling, and adipose-tissue biology.

How does tirzepatide compare with semaglutide?

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Semaglutide activates only the GLP-1 receptor; tirzepatide also activates the GIP receptor. In reported animal studies the dual profile produces a stronger metabolic effect than single-receptor analogs. Our comparison article covers the mechanisms side by side.

How does tirzepatide compare with retatrutide?

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Retatrutide adds activity at the glucagon receptor to the GLP-1 and GIP activity that tirzepatide has. That third receptor is the basis of research into energy expenditure and hepatic lipid handling.

Which tirzepatide vial size should I choose?

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QSC supplies 5, 10, 15, 20, 30, 40, 50, 60, 80, 100 and 120 mg vials. Choose by stock concentration and how quickly you will use the solution: a 10 mg vial in 2 mL gives 5 mg/mL, and a 60 mg vial in 6 mL gives 10 mg/mL. Check the vial capacity before adding solvent.

How do I reconstitute and store tirzepatide?

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Reconstitution is typically at 5 to 10 mg/mL in sterile water depending on protocol. The acetate counterion content is reflected on the COA, so adjust for effective peptide content if your protocol calls for it. Keep lyophilized powder at -20°C for long-term storage and refrigerate after reconstitution.

What tirzepatide blends are available?

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Pre-mixed research blends are available with cagrilintide (10 mg and 20 mg vials) and with retatrutide (a 1:1 blend, 30 mg of each per 60 mg vial). Each is a single reconstitution step for protocols that use both compounds.

Are prices per vial or per pack?

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Prices are per 10-vial pack of one size. Email us to arrange a smaller order at the same per-vial price. Orders of $1,000 or more ship free, and delivery is typically about 10 to 15 days, duties paid.

Is tirzepatide approved for human use?

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The research-grade material QSC supplies is not approved for human or veterinary use and is sold strictly for laboratory research. Nothing on this site is medical advice.

Published by QSC Peptidology for research-community reference. Not medical advice, and not a recommendation for human or veterinary use. All products are sold strictly for laboratory and research use only.