Gonadorelin Research Hub

Gonadorelin is the native-sequence gonadotropin-releasing hormone (GnRH, LHRH) decapeptide. It stimulates pituitary release of LH and FSH and is used in research on the hypothalamic-pituitary-gonadal axis. CAS 33515-09-2; molecular weight about 1182 Da.

Yes. Gonadorelin is the name for the native-sequence GnRH decapeptide, so the terms GnRH, LHRH, and gonadorelin refer to the same sequence. Other GnRH analogs have modified sequences and longer half-lives.

Because the GnRH receptor responds differently to pulses than to sustained exposure. Pulsatile exposure keeps the receptor responsive and LH and FSH release continuing, while continuous exposure leads to receptor desensitisation and a falling response. Gonadorelin's half-life of minutes is why protocols use pulses.

Reconstitute the lyophilized powder in sterile or bacteriostatic water at a concentration suited to your protocol. Concentration equals the milligrams in the vial divided by the millilitres of solvent, so a 5 mg vial in 5 mL gives 1 mg/mL. Swirl gently, and refrigerate after reconstitution.

Keep lyophilized powder at -20°C for long-term storage. Because the peptide is short-lived in solution, divide the reconstituted solution into single-use aliquots, refrigerate, and avoid repeated freeze-thaw cycles.

Choose by how quickly you will use the reconstituted solution. The 2 mg vial limits waste in small or slow protocols; the 5 mg vial suits many replicates in a short period. Each 10-vial pack contains ten identical vials from one lot.

Prices are per 10-vial pack of one size. Email us to arrange a smaller order at the same per-vial price. Orders of $1,000 or more ship free, and delivery is typically about 10 to 15 days, duties paid.

The research-grade material QSC supplies is not approved for human or veterinary use and is sold strictly for laboratory research. Nothing on this site is medical advice.